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PREMARIN 1.25mg 28s TABLET
ZMK 610.00
MRP 705.00
Includes all taxes
Item requires a valid prescription
Composition: Each tablet contains 1.25mg conjugated estrogens.
Hormone replacement therapy
Description:
Premarin is an estrogen only Hormone Replacement Therapy.
Uses / Indications:
It is used for hormone replacement therapy for estrogen deficiency symptoms in postmenopausal women. It is used for Prevention of osteoporosis in postmenopausal women at high risk of future fractures who are intolerant of, or contraindicated for, other medicinal products approved for the prevention of osteoporosis.
Pregnancy interaction:
Premarin is not indicated during pregnancy
Side Effects:
Common side effects are Depression, Alopecia, Arthralgias, Leg cramps, Abnormal uterine bleeding (Breakthrough bleeding/spotting); Breast pain, tenderness, enlargement, discharge; Leucorrhoea,
How to use:
Premarin 0.3-1.25mg daily is the usual starting dose for women without a uterus. Continuous administration is recommended. Treatment to control menopausal symptoms should be initiated with Premarin 0.3mg. If symptoms are not adequately controlled, higher doses of Premarin may be prescribed. Once treatment is established the lowest effective dose necessary for the relief of symptoms should be used. Patients should be re-evaluated periodically to determine if treatment for symptoms is still necessary.
How it works:
Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. Although circulating estrogens exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol, at the receptor level.
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